An interesting review on the use of CIM (complementary and integrative medicine) in three conditions with a high incidence of chronic pain: back pain, neck pain, and rheumatoid arthritis, was recently published in the BMJ.
The ‘Who To Treat with Statins’ debate still rages, with two different (main) guidelines in the USA recommending slightly different groups to be treated. Government-backed U.S. Preventive Services Task Force (USPSTF) set a higher threshold for use of the drugs, known as statins, than the American College of Cardiology and the American Heart Association (ACC/AHA).
The FDA has advised that for children younger than 12, codeine is now contraindicated for the management of pain or cough, as is tramadol for pain. This is due to the fact that some people have a variation in their CYP2D6 enzymes which makes them metabolise drugs that are substrates of CYP2D6 very rapidly.
A recent systematic review found no benefit for the use of cannabinoids in the management of acute pain. Conversely, a number of systematic reviews have suggested that cannabinoids are beneficial in the management of chronic pain.